Standard No.:	GB/T 29675-2013
English Name:	Determination of nonylphenol in cosmetics—Liquid chromatography tandem mass spectrometry
Chinese Name:	化妆品中壬基苯酚的测定 液相色谱-质谱/质谱法
Chinese Classification:	Y42    Cosmetics
Professional Classification:	GB    National Standard
ICS Classification:	71.100.70 71.100.70    Cosmetics. Toiletries 71.100.70
Source Content Issued by:	AQSIQ;SAC
Issued on:	2013-9-6
Implemented on:	2014-2-15
Status:	valid
Target Language:	English
File Format:	PDF
Word Count:	6000 words
Translation Price(USD):	180.0
Delivery:	via email in 1~3 business day

1 Scope This standard specifies liquid chromatography tandem mass spectrometry of nonylphenol in cosmetics. This standard applies to the determination of nonylphenol in such cosmetics as cream, loose powder, waters and lipstick. For the purpose of this standard, the detection limit and quantitation limit of nonylphenol are 0.1 mg/kg and 0.2 mg/kg respectively. 2 Normative References The following documents are indispensable for application of this standard. Any dated reference, only dated edition applies. For the undated reference, the latest edition (including any amendments) applies. GB/T 6682 Water for Analytical Laboratory Use - Specification and Test Methods 3 Principle Extract nonylphenol in cosmetics with methyl alcohol - methylene chloride mixed solution, purify the extracting solution by centrifugation and solid-phase extraction column, determine by liquid chromatography tandem mass spectrometry and quantify by internal standard method. 4 Reagents and Materials

Foreword i Introduction ii 1 Scope 2 Normative References 3 Principle 4 Reagents and Materials 5 Apparatus 6 Determination Procedure 7 Result Calculation 8 Detection Limit and Quantitation Limit 9 Recovery Rate and Precision 10 Permissible Deviation Annex A (Informative) Structural Formula of Nonylphenol Standard Annex B (Informative) Selected Iron Mass Chromatogram of Nonylphenol Standard and Internal Standard Substance