Standard No.:	GB 30000.22-2013
English Name:	Rules for classification and labelling of chemicals—Part 22:Germ cell mutagenicity
Chinese Name:	化学品分类和标签规范 第22部分：生殖细胞致突变性
Chinese Classification:	A80    Marking, packaging, transport and storage in general
Professional Classification:	GB    National Standard
Source Content Issued by:	AQSIQ;SAC
Issued on:	2013-10-10
Implemented on:	2014-11-1
Status:	valid
Superseding:	GB 20596-2006 Safety rules for classification, precautionary labelling and precautionary statements of chemicals - Germ cell mutagenicity
Target Language:	English
File Format:	PDF
Word Count:	9000 words
Translation Price(USD):	270.0
Delivery:	via email in 1 business day

The expected structure of GB 30000 Rules for Classification and Labelling of Chemicals and the national standards to be replaced are: ——Part 1: General (replaces GB 13690-2009); ——Part 2: Explosives (replaces GB 20576-2006); ——Part 3: Flammable gases (replaces GB 20577-2006); ——Part 4: Aerosol (replaces GB 20578-2006); ——Part 5: Oxidizing gases (replaces GB 20579-2006); ——Part 6: Gases under pressure (replaces GB 20580-2006); ——Part 7: Flammable liquids (replaces GB 20581-2006); ——Part 8: Flammable solids (replaces GB 20582-2006); ——Part 9: Self-reactive substances and mixtures (replaces GB 20583-2006); ——Part 10: Pyrophoric liquids (replaces GB 20585-2006); ——Part 11: Pyrophoric solids (replaces GB 20586-2006); ——Part 12: Self-reactive substances and mixtures (replaces GB 20584-2006); ——Part 13: Substances and mixtures which, in contact with water, emit flammable gases (replaces GB 20587-2006); ——Part 14: Oxidizing liquids (replaces GB 20589-2006); ——Part 15: Oxidizing solids (replaces GB 20590-2006); ——Part 16: Organic peroxides (replaces GB 20591-2006); ——Part 17: Corrosive to metals (replaces GB 20588-2006); ——Part 18: acute toxicity (replaces GB 20592-2006); ——Part 19: Skin corrosion/irritation (replaces GB 20593-2006); ——Part 20: Serious eye damage/eye irritation (replaces GB 20594-2006); ——Part 21: Respiratory or skin sensitization (replaces GB 20595-2006); ——Part 22: Germ cell mutagenicity (replaces GB 20596-2006); ——Part 23: Carcinogenicity (replaces GB 20597-2006); ——Part 24: Reproductive toxicity (replaces GB 20598-2006); ——Part 25: Specific target organ toxicity - Single exposure (replaces GB 20599-2006); ——Part 26: Specific target organ toxicity - Repeated exposure (replaces GB 20601-2006); ——Part 27: Aspiration hazard; ——Part 28: Hazardous to the aquatic environment (replaces GB 20602-2006); ——Part 29: Hazardous to the ozone layer; ——Part 30: Warning Signs in Chemical Workplaces; This is Part 22 of GB 30000. 1 Scope This part of GB 30000 stipulates the terms and definitions, classification standards, judgment logic and guidance and labels of chemicals with germ cell mutagenicity. This part is applicable to the classification and labelling of chemicals with germ cell mutagenicity according to the United Nations Globally Harmonized System of Classification and Labelling of Chemicals (GHS). 2 Normative references The following referenced documents are indispensable for the application of this document. For dated references, only the edition cited applies. For undated references, the latest edition of the referenced document (including any amendments) applies. GB 30000.23 Rules for classification and labelling of chemicals - Part 23: Carcinogenicity GB 13690 General rule for classification and hazard communication of chemicals The United Nations Globally Harmonized System of Classification and Labelling of Chemicals (GHS) (Rev.4) The United Nations Recommendations on the transport of dangerous goods: Model regulations (Rev.17) 3 Terms and definitions For the purposes of this document, the terms and definitions given in GB 13690 and the following apply. 3.1 germ cell mutagenicity Chemicals cause mutations in human germ cells that may be passed on to future generations. When classifying substances and mixtures into this hazard category, pay attention to in vitro mutagenicity/genotoxicity test and in vivo mutagenicity and genotoxicity test of mammalian somatic cells. In this standard, terms mutagenicity, mutagen, mutation and genotoxicity will be mentioned many times. "Mutation" is defined as a permanent change in the quantity or structure of genetic material in cells. The term "mutation" is applicable to dominant heritable genetic changes and potential DNA modifications (for example, known specific base-pairs transformation and chromosome translocation). The terms "mutagenicity" and "mutagen" apply to substances that cause an increase in the incidence of mutations in cells and/or organism communities.

Foreword i 1 Scope 2 Normative references 3 Terms and definitions 4 Classification standards 5 Judgment logic and guidance 6 Labelling Annex A (Informative) Judgment logic and guidance Annex B (Normative) Allocation of label elements Annex C (Normative) Classification standards and label elements of germ cell mutagenicity Annex D (Informative) Hazard statement and precautionary statement of germ cell mutagenicity Annex E (Informative) Label example of germ cell mutagenicity Annex F (Informative) Test items and standards related to germ cell mutagenicity